Every once in a while we will play more traditional family party games like Pictionary, Guesstures, and Cranium. Cranium is particularly popular with the boys, especially the kids version Cranium Cadoo. Cranium is particularly fun since it incorporates a number of different skills - sculpting, trivia, drawing, charades, and more.
Anyway, to the point: Cranium is offering online the ability to make custom Cranium cards. These are theme-oriented, downloadable (PDF) card sets that you can customize for your game. I particularly like the family-oriented theme - give it a try!